Reaction Details Report a problem with these data
Target
UDP-glucuronosyltransferase 2B7
Ligand
BDBM50183609
Substrate
n/a
Meas. Tech.
ChEMBL_339082 (CHEMBL869546)
Ki
624000±n/a nM
Citation
 Bichlmaier, I; Siiskonen, A; Finel, M; Yli-Kauhaluoma, J Stereochemical sensitivity of the human UDP-glucuronosyltransferases 2B7 and 2B17. J Med Chem 49:1818-27 (2006) [PubMed]  Article 
Target
Name:
UDP-glucuronosyltransferase 2B7
Synonyms:
2.4.1.17 | 3,4-catechol estrogen-specific UDPGT | UD2B7_HUMAN | UDP-glucuronosyltransferase 2B7 | UDP-glucuronosyltransferase 2B9 | UDPGT 2B7 | UDPGT 2B9 | UDPGTh-2 | UGT2B7 | UGTB2B9 | Uridine-5'-diphosphoglucuronosyltransferase 2B7
Type:
Enzyme
Mol. Mass.:
60705.98
Organism:
Homo sapiens (Human)
Description:
P16662
Residue:
529
Sequence:
MSVKWTSVILLIQLSFCFSSGNCGKVLVWAAEYSHWMNIKTILDELIQRGHEVTVLASSASILFDPNNSSALKIEIYPTSLTKTELENFIMQQIKRWSDLPKDTFWLYFSQVQEIMSIFGDITRKFCKDVVSNKKFMKKVQESRFDVIFADAIFPCSELLAELFNIPFVYSLSFSPGYTFEKHSGGFIFPPSYVPVVMSELTDQMTFMERVKNMIYVLYFDFWFEIFDMKKWDQFYSEVLGRPTTLSETMGKADVWLIRNSWNFQFPYPLLPNVDFVGGLHCKPAKPLPKEMEDFVQSSGENGVVVFSLGSMVSNMTEERANVIASALAQIPQKVLWRFDGNKPDTLGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTMSSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLVCVATVIFIVTKCCLFCFWKFARKAKKGKND
  
Inhibitor
Name:
BDBM50183609
Synonyms:
(rac)-6-methyl-2,3-dihydro-1H-inden-1-ol | CHEMBL202791
Type:
Small organic molecule
Emp. Form.:
C10H12O
Mol. Mass.:
148.2017
SMILES:
Cc1ccc2CCC(O)c2c1
Structure:
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