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Target
N-formyl peptide receptor 2
Ligand
BDBM31710
Substrate
n/a
Meas. Tech.
ChEMBL_376306 (CHEMBL867962)
EC50
490±n/a nM
Citation
 Bürli, RW; Xu, H; Zou, X; Muller, K; Golden, J; Frohn, M; Adlam, M; Plant, MH; Wong, M; McElvain, M; Regal, K; Viswanadhan, VN; Tagari, P; Hungate, R Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agents. Bioorg Med Chem Lett 16:3713-8 (2006) [PubMed]  Article 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM31710
Synonyms:
1-(4-chlorophenyl)-3-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazol-4-yl)urea | 1-(4-chlorophenyl)-3-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)urea | 1-(4-chlorophenyl)-3-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)urea | 1-(4-chlorophenyl)-3-(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)urea | CHEMBL210298 | MLS000107112 | SMR000111484 | cid_1367800
Type:
Small organic molecule
Emp. Form.:
C18H17ClN4O2
Mol. Mass.:
356.806
SMILES:
Cc1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2ccccc2)n1C
Structure:
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