Reaction Details Report a problem with these data
Target
Vasoactive intestinal polypeptide receptor 2
Ligand
BDBM50435130
Substrate
n/a
Meas. Tech.
ChEMBL_2260453 (CHEMBL5215464)
EC50
0.080000±n/a nM
Citation
 Hu, E; Hong, FT; Aral, J; Long, J; Piper, DE; Poppe, L; Andrews, KL; Hager, T; Davis, C; Li, H; Wong, P; Gavva, N; Shi, L; Zhu, DXD; Lehto, SG; Xu, C; Miranda, LP Discovery of Selective Pituitary Adenylate Cyclase 1 Receptor (PAC1R) Antagonist Peptides Potent in a Maxadilan/PACAP38-Induced Increase in Blood Flow Pharmacodynamic Model. J Med Chem 64:3427-3438 (2021) [PubMed] 
Target
Name:
Vasoactive intestinal polypeptide receptor 2
Synonyms:
VIP 2 | VIP2R | VIPR2 | VIPR2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49488.30
Organism:
Homo sapiens (Human)
Description:
VIP 2 VIPR2 HUMAN::P41587
Residue:
438
Sequence:
MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGSSFSRNGSEGALQFHRGSRAQSFLQTETSVI
  
Inhibitor
Name:
BDBM50435130
Synonyms:
CHEMBL1893324
Type:
Small organic molecule
Emp. Form.:
C147H238N44O42S
Mol. Mass.:
3325.797
SMILES:
n/a
Structure:
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