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Target
Cyclin-dependent kinase 17
Ligand
BDBM50593922
Substrate
n/a
Meas. Tech.
ChEMBL_2264716
IC50
>1200±n/a nM
Citation
 Huang, Z; Wang, T; Wang, C; Fan, Y CDK9 inhibitors in cancer research. RSC Med Chem 13:688-710 (2022) [PubMed] 
Target
Name:
Cyclin-dependent kinase 17
Synonyms:
CDK17 | CDK17_HUMAN | PCTAIRE2 | PCTK2 | Serine/threonine-protein kinase PCTAIRE-2
Type:
PROTEIN
Mol. Mass.:
59600.69
Organism:
Homo sapiens (Human)
Description:
ChEMBL_586854
Residue:
523
Sequence:
MKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEVQSPTGVCLRNRIHRRISMEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHGKNRRQSMLF
  
Inhibitor
Name:
BDBM50593922
Synonyms:
CHEMBL5199065
Type:
Small organic molecule
Emp. Form.:
C16H25N5
Mol. Mass.:
287.4032
SMILES:
CCC(CC)c1cc(N[C@H]2CC[C@H](N)C2)n2nccc2n1 |r|
Structure:
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