Reaction Details Report a problem with these data
Target
P2Y purinoceptor 6
Ligand
BDBM50405433
Substrate
n/a
Meas. Tech.
ChEMBL_2265211
IC50
4090±n/a nM
Citation
 Jung, YH; Shah, Q; Lewicki, SA; Pramanik, A; Gopinatth, V; Pelletier, J; Sévigny, J; Iqbal, J; Jacobson, KA Synthesis and pharmacological characterization of multiply substituted 2H-chromene derivatives as P2Y Bioorg Med Chem Lett 75:0 (2022) [PubMed] 
Target
Name:
P2Y purinoceptor 6
Synonyms:
P2RY6 | P2RY6_HUMAN | P2Y purinoceptor 6 | P2Y6 | Pyrimidinergic receptor P2Y6
Type:
PROTEIN
Mol. Mass.:
36452.29
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1511151
Residue:
328
Sequence:
MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAKWQRQGR
  
Inhibitor
Name:
BDBM50405433
Synonyms:
CHEMBL5283029
Type:
Small organic molecule
Emp. Form.:
C10H5F3INO3
Mol. Mass.:
371.0513
SMILES:
[O-][N+](=O)C1=Cc2cccc(I)c2OC1C(F)(F)F |t:3|
Structure:
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