Reaction Details Report a problem with these data
Target
Sortase family protein
Ligand
BDBM50410879
Substrate
n/a
Meas. Tech.
ChEMBL_2268803
IC50
13±n/a nM
Citation
 Sapra, R; Rajora, AK; Kumar, P; Maurya, GP; Pant, N; Haridas, V Chemical Biology of Sortase A Inhibition: A Gateway to Anti-infective Therapeutic Agents. J Med Chem 64:13097-13130 (2021) [PubMed] 
Target
Name:
Sortase family protein
Synonyms:
Sortase | Sortase A (SrtA)
Type:
Enzyme
Mol. Mass.:
23546.15
Organism:
Staphylococcus aureus
Description:
n/a
Residue:
206
Sequence:
MKKWTNRLMTIAGVVLILVAAYLFAKPHIDNYLHDKDKDEKIEQYDKNVKEQASKDKKQQAKPQIPKDKSKVAGYIEIPDADIKEPVYPGPATPEQLNRGVSFAEENESLDDQNISIAGHTFIDRPNYQFTNLKAAKKGSMVYFKVGNETRKYKMTSIRDVKPTDVGVLDEQKGKDKQLTLITCDDYNEKTGVWEKRKIFVATEVK
  
Inhibitor
Name:
BDBM50410879
Synonyms:
CHEMBL5268777
Type:
Small organic molecule
Emp. Form.:
C23H22ClNO4
Mol. Mass.:
411.878
SMILES:
[Cl-].COc1ccc2cc3-c4cc(C(C)=O)c(cc4CC[n+]3cc2c1OC)C(C)=O
Structure:
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