Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50194816
Substrate
n/a
Meas. Tech.
ChEMBL_424567 (CHEMBL913647)
Ki
>10000±n/a nM
Citation
 Richardson, CM; Gillespie, RJ; Williamson, DS; Jordan, AM; Fink, A; Knight, AR; Sellwood, DM; Misra, A Identification of non-furan containing A2A antagonists using database mining and molecular similarity approaches. Bioorg Med Chem Lett 16:5993-7 (2006) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50194816
Synonyms:
CHEMBL221219 | N-(4-fluorobenzyl)-4-phenyl-6-(trifluoromethyl)pyrimidin-2-amine
Type:
Small organic molecule
Emp. Form.:
C18H13F4N3
Mol. Mass.:
347.3095
SMILES:
Fc1ccc(CNc2nc(cc(n2)C(F)(F)F)-c2ccccc2)cc1
Structure:
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