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Target
Programmed cell death 1 ligand 2
Ligand
BDBM50587706
Substrate
n/a
Meas. Tech.
ChEMBL_2273455
EC50
149±n/a nM
Citation
 Lin, X; Lu, X; Luo, G; Xiang, H Progress in PD-1/PD-L1 pathway inhibitors: From biomacromolecules to small molecules. Eur J Med Chem 186:0 (2020) [PubMed] 
Target
Name:
Programmed cell death 1 ligand 2
Synonyms:
B7-DC | B7DC | Butyrophilin B7-DC | CD273 | CD_antigen=CD273 | PD-1 ligand 2 | PD-L2 | PD1L2_HUMAN | PDCD1 ligand 2 | PDCD1L2 | PDCD1LG2 | PDL2 | Programmed cell death 1 ligand 2 | Programmed death ligand 2
Type:
PROTEIN
Mol. Mass.:
30963.56
Organism:
Homo sapiens
Description:
ChEMBL_114967
Residue:
273
Sequence:
MIFLLLMLSLELQLHQIAALFTVTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQKVENDTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFIPFCIIAFIFIATVIALRKQLCQKLYSSKDTTKRPVTTTKREVNSAI
  
Inhibitor
Name:
BDBM50587706
Synonyms:
CHEMBL5197008
Type:
Small organic molecule
Emp. Form.:
C12H20N6O6S
Mol. Mass.:
376.389
SMILES:
CC(O)[C@H](NC(=O)N[C@@H](CC(N)=O)c1nnc(s1)[C@@H](N)CO)C(O)=O |r|
Structure:
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