Reaction Details Report a problem with these data
Target
Stimulator of interferon genes protein
Ligand
BDBM50610502
Substrate
n/a
Meas. Tech.
ChEMBL_2281197
Kd
130±n/a nM
Citation
 Zhang, J; Zhang, Y; Qu, B; Yang, H; Hu, S; Dong, X If small molecules immunotherapy comes, can the prime be far behind? Eur J Med Chem 218:0 (2021) [PubMed] 
Target
Name:
Stimulator of interferon genes protein
Synonyms:
Endoplasmic reticulum interferon stimulator | Eris | MMITA | Mediator of IRF3 activation | Mita | Mpys | STING_MOUSE | Stimulator of interferon genes protein | Sting | Sting1 | Synonyms=Eris | Tmem173 | Transmembrane protein 173 | mSTING
Type:
PROTEIN
Mol. Mass.:
42834.49
Organism:
Mus musculus
Description:
ChEMBL_119061
Residue:
378
Sequence:
MPYSNLHPAIPRPRGHRSKYVALIFLVASLMILWVAKDPPNHTLKYLALHLASHELGLLLKNLCCLAEELCHVQSRYQGSYWKAVRACLGCPIHCMAMILLSSYFYFLQNTADIYLSWMFGLLVLYKSLSMLLGLQSLTPAEVSAVCEEKKLNVAHGLAWSYYIGYLRLILPGLQARIRMFNQLHNNMLSGAGSRRLYILFPLDCGVPDNLSVVDPNIRFRDMLPQQNIDRAGIKNRVYSNSVYEILENGQPAGVCILEYATPLQTLFAMSQDAKAGFSREDRLEQAKLFCRTLEEILEDVPESRNNCRLIVYQEPTDGNSFSLSQEVLRHIRQEEKEEVTMNAPMTSVAPPPSVLSQEPRLLISGMDQPLPLRTDLI
  
Inhibitor
Name:
BDBM50610502
Synonyms:
CHEMBL166512
Type:
Small organic molecule
Emp. Form.:
C16H12O4
Mol. Mass.:
268.2641
SMILES:
Cc1ccc2c(c1)oc1c(CC(O)=O)cccc1c2=O
Structure:
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