Reaction Details Report a problem with these data
Target
Aminodeoxyfutalosine nucleosidase
Ligand
BDBM36436
Substrate
n/a
Meas. Tech.
ChEMBL_2281820
Kd
<50±n/a nM
Citation
 Ghobadi, E; Ghanbarimasir, Z; Emami, S A review on the structures and biological activities of anti-Helicobacter pylori agents. Eur J Med Chem 223:0 (2021) [PubMed] 
Target
Name:
Aminodeoxyfutalosine nucleosidase
Synonyms:
3.2.2.30 | 3.2.2.9 | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 6-amino-6-deoxyfutalosine N-ribosylhydrolase | AFL nucleosidase | Aminodeoxyfutalosine nucleosidase | Aminofutalosine nucleosidase | MTA/SAH nucleosidase | MTAN | mtn | mtnN
Type:
PROTEIN
Mol. Mass.:
25015.59
Organism:
Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Description:
ChEMBL_120894
Residue:
230
Sequence:
MQKIGILGAMREEITPILELFGVDFEEIPLGGNVFHKGVYHNKEIIVAYSKIGKVHSTLTTTSMILAFGVQKVLFSGVAGSLVKDLKINDLLVATQLVQHDVDLSAFDHPLGFIPESAIFIETSGSLNALAKKIANEQHIALKEGVIASGDQFVHSKERKEFLVSEFKASAVEMEGASVAFVCQKFGVPCCVLRSISDNADEKAGMSFDEFLEKSAHTSAKFLKSMVDEL
  
Inhibitor
Name:
BDBM36436
Synonyms:
(3R,4S)-1-[(9-Deaza-adenin-9-yl)methyl]-4-ethylthio-methyl-3-hydroxypyrrolidine, 9 | (3R,4S)-4-(1-Butylthiomethyl)-1-[(9-deaza-adenin-9-yl)methyl]-3-hydroxypyrrolidine, 9 | CID11393519
Type:
Small organic molecule
Emp. Form.:
C16H25N5OS
Mol. Mass.:
335.468
SMILES:
CCCCSC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O
Structure:
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