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Target
Beta-2 adrenergic receptor
Ligand
BDBM50036840
Substrate
n/a
Meas. Tech.
ChEMBL_2286926
Ki
1260±n/a nM
Citation
 Subbaiah, MAM; Meanwell, NA Bioisosteres of the Phenyl Ring: Recent Strategic Applications in Lead Optimization and Drug Design. J Med Chem 64:14046-14128 (2021) [PubMed] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2_BOVIN | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor | adrenergic Beta
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47141.18
Organism:
BOVINE
Description:
adrenergic Beta ADRB2 BOVINE::Q28044
Residue:
418
Sequence:
MGQPGNRSVFLLAPNASHAPDQNVTLERDEAWVVGMGILMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGACHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYLAITSPFKYQCLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRASHKEAINCYAKETCCDFFTNQPYAIASSIVSFYLPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNVSQVEQDGRSGLGQRRTSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIKDNLIRKEIYILLNWLGYINSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGCSSNSNDRTDYTGEQSGYHLGEEKDSELLCEDPPGTENFVNQQGTVPSDSIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50036840
Synonyms:
CHEMBL38033 | Propionaldehyde O-(3-tert-butylamino-2-hydroxy-propyl)-oxime; compound with (E)-but-2-enedioic acid
Type:
Small organic molecule
Emp. Form.:
C10H22N2O2
Mol. Mass.:
202.2939
SMILES:
CC\C=N\OCC(O)CNC(C)(C)C
Structure:
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