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Target
D(1B) dopamine receptor
Ligand
BDBM50201337
Substrate
n/a
Meas. Tech.
ChEMBL_453888 (CHEMBL885890)
Ki
0.23±n/a nM
Citation
 Enzensperger, C; Kilian, S; Ackermann, M; Koch, A; Kelch, K; Lehmann, J Dopamine/serotonin receptor ligands. Part 15: Oxygenation of the benz-indolo-azecine LE 300 leads to novel subnanomolar dopamine D1/D5 antagonists. Bioorg Med Chem Lett 17:1399-402 (2007) [PubMed]  Article 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM50201337
Synonyms:
11-methoxy-7,14-dimethyl-6,7,8,9,14,15-hexahydro-5Hindolo[3,2-f][3]benzazecine | CHEMBL245764
Type:
Small organic molecule
Emp. Form.:
C22H26N2O
Mol. Mass.:
334.4546
SMILES:
COc1ccc2n(C)c3Cc4ccccc4CCN(C)CCc3c2c1
Structure:
Search PDB for entries with ligand similarity: