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Target
Mu-type opioid receptor
Ligand
BDBM50207195
Substrate
n/a
Meas. Tech.
ChEMBL_443023 (CHEMBL892154)
IC50
610±n/a nM
Citation
 Balboni, G; Onnis, V; Congiu, C; Zotti, M; Sasaki, Y; Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Lazzari, I; Trapella, C; Salvadori, S Further studies on the effect of lysine at the C-terminus of the Dmt-Tic opioid pharmacophore. Bioorg Med Chem 15:3143-51 (2007) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50207195
Synonyms:
(S)-N-((S)-5-acetamido-5-(1H-benzo[d]imidazol-2-yl)pentyl)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide | CHEMBL397357
Type:
Small organic molecule
Emp. Form.:
C35H42N6O4
Mol. Mass.:
610.7458
SMILES:
CC(=O)N[C@@H](CCCCNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1nc2ccccc2[nH]1
Structure:
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