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Target
Beta-lactamase
Ligand
BDBM31770
Substrate
n/a
Meas. Tech.
ChEMBL_434808 (CHEMBL917036)
IC50
100000±n/a nM
Citation
 Feng, BY; Simeonov, A; Jadhav, A; Babaoglu, K; Inglese, J; Shoichet, BK; Austin, CP A high-throughput screen for aggregation-based inhibition in a large compound library. J Med Chem 50:2385-90 (2007) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC
Type:
Protien
Mol. Mass.:
41561.62
Organism:
Escherichia coli
Description:
P00811
Residue:
377
Sequence:
MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSIINGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNYPNPARVDAAWQILNALQ
  
Inhibitor
Name:
BDBM31770
Synonyms:
Exelderm | Sulconazole Nitrate | cid_65495 | sulconazole
Type:
Small organic molecule
Emp. Form.:
C18H15Cl3N2S
Mol. Mass.:
397.749
SMILES:
Clc1ccc(CSC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1
Structure:
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