Reaction Details Report a problem with these data
Target
Glyoxalase I
Ligand
BDBM50213421
Substrate
n/a
Meas. Tech.
ChEMBL_456126 (CHEMBL888135)
Ki
112440±n/a nM
Citation
 More, SS; Vince, R Design, synthesis, and binding studies of bidentate Zn-chelating peptidic inhibitors of glyoxalase-I. Bioorg Med Chem Lett 17:3793-7 (2007) [PubMed]  Article 
Target
Name:
Glyoxalase I
Synonyms:
GLO1 | LGUL_YEAST | Lactoylglutathione lyase
Type:
PROTEIN
Mol. Mass.:
37210.98
Organism:
Saccharomyces cerevisiae
Description:
ChEMBL_571116
Residue:
326
Sequence:
MSTDSTRYPIQIEKASNDPTLLLNHTCLRVKDPARTVKFYTEHFGMKLLSRKDFEEAKFSLYFLSFPKDDIPKNKNGEPDVFSAHGVLELTHNWGTEKNPDYKINNGNEEPHRGFGHICFSVSDINKTCEELESQGVKFKKRLSEGRQKDIAFALGPDGYWIELITYSREGQEYPKGSVGNKFNHTMIRIKNPTRSLEFYQNVLGMKLLRTSEHESAKFTLYFLGYGVPKTDSVFSCESVLELTHNWGTENDPNFHYHNGNSEPQGYGHICISCDDAGALCKEIEVKYGDKIQWSPKFNQGRMKNIAFLKDPDGYSIEVVPHGLIA
  
Inhibitor
Name:
BDBM50213421
Synonyms:
(S)-2-amino-5-((S)-1-(carboxymethylamino)-7-methoxy-1,5,7-trioxoheptan-2-ylamino)-5-oxopentanoic acid | CHEMBL438862
Type:
Small organic molecule
Emp. Form.:
C15H23N3O9
Mol. Mass.:
389.3578
SMILES:
COC(=O)CC(=O)CC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O
Structure:
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