Reaction Details Report a problem with these data
Target
Casein kinase II subunit alpha
Ligand
BDBM50214472
Substrate
n/a
Meas. Tech.
ChEMBL_439083 (CHEMBL889431)
Ki
260±n/a nM
Citation
 Nie, Z; Perretta, C; Erickson, P; Margosiak, S; Almassy, R; Lu, J; Averill, A; Yager, KM; Chu, S Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg Med Chem Lett 17:4191-5 (2007) [PubMed]  Article 
Target
Name:
Casein kinase II subunit alpha
Synonyms:
ACK2 | CK II | CK2- alpha | CSK2A_MAIZE | Casein Kinase II
Type:
Enzyme
Mol. Mass.:
39238.74
Organism:
Zea mays (Maize)
Description:
n/a
Residue:
332
Sequence:
MSKARVYADVNVLRPKEYWDYEALTVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEKCIIKILKPVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYVNNTDFKVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTDGLNVYLNKYRIELDPQLEALVGRHSRKPWLKFMNADNQHLVSPEAIDFLDKLLRYDHQERLTALEAMTHPYFQQVRAAENSRTRA
  
Inhibitor
Name:
BDBM50214472
Synonyms:
CHEMBL231095 | N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE | N2,N4-diphenylpyrazolo[1,5-a][1,3,5]triazine-2,4-diamine
Type:
Small organic molecule
Emp. Form.:
C17H14N6
Mol. Mass.:
302.3333
SMILES:
N(c1ccccc1)c1nc(Nc2ccccc2)n2nccc2n1
Structure:
Search PDB for entries with ligand similarity: