Reaction Details Report a problem with these data
Target
Solute carrier family 2, facilitated glucose transporter member 1
Ligand
BDBM50216465
Substrate
n/a
Meas. Tech.
ChEMBL_456667 (CHEMBL924048)
Ki
>500000±n/a nM
Citation
 Ionita, M; Krishna, S; Léo, PM; Morin, C; Patel, AP Interaction of O-(undec-10-en)-yl-D-glucose derivatives with the Plasmodium falciparum hexose transporter (PfHT). Bioorg Med Chem Lett 17:4934-7 (2007) [PubMed]  Article 
Target
Name:
Solute carrier family 2, facilitated glucose transporter member 1
Synonyms:
GLUT-1 | GLUT1 | GTR1_HUMAN | Glucose Transporter 1 (hGLUT1) | Glucose transporter | Glucose transporter type 1, erythrocyte/brain | HepG2 glucose transporter | SLC2A1
Type:
Protein
Mol. Mass.:
54091.71
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
492
Sequence:
MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEELFHPLGADSQV
  
Inhibitor
Name:
BDBM50216465
Synonyms:
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(undec-10-enyloxy)-tetrahydro-2H-pyran-3,4,5-triol | CHEMBL248915
Type:
Small organic molecule
Emp. Form.:
C17H32O6
Mol. Mass.:
332.4324
SMILES:
OC[C@H]1O[C@@H](OCCCCCCCCCC=C)[C@H](O)[C@@H](O)[C@@H]1O
Structure:
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