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Target
Cannabinoid receptor 2
Ligand
BDBM50228075
Substrate
n/a
Meas. Tech.
ChEMBL_452383 (CHEMBL901623)
Ki
4.8±n/a nM
Citation
 Khanolkar, AD; Lu, D; Ibrahim, M; Duclos, RI; Thakur, GA; Malan, TP; Porreca, F; Veerappan, V; Tian, X; George, C; Parrish, DA; Papahatjis, DP; Makriyannis, A Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity. J Med Chem 50:6493-500 (2007) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38220.43
Organism:
MOUSE
Description:
P47936
Residue:
347
Sequence:
MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
  
Inhibitor
Name:
BDBM50228075
Synonyms:
6,6-dimethyl-3-(1',1'-dimethylheptyl)-6H-benzo[c]chromene-1,9-diol | AM-4768 | CHEMBL238359
Type:
Small organic molecule
Emp. Form.:
C24H32O3
Mol. Mass.:
368.5091
SMILES:
CCCCCCC(C)(C)c1cc(O)c-2c(OC(C)(C)c3ccc(O)cc-23)c1
Structure:
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