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Target
Cannabinoid receptor 1
Ligand
BDBM50061113
Substrate
n/a
Meas. Tech.
ChEMBL_452382 (CHEMBL901622)
Ki
0.95±n/a nM
Citation
 Khanolkar, AD; Lu, D; Ibrahim, M; Duclos, RI; Thakur, GA; Malan, TP; Porreca, F; Veerappan, V; Tian, X; George, C; Parrish, DA; Papahatjis, DP; Makriyannis, A Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity. J Med Chem 50:6493-500 (2007) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50061113
Synonyms:
3-(1',1'-dimethylheptyl)-6,6,9-trimethyl-6H-benzo[c]chromene-1-ol | 3-(1,1-Dimethyl-heptyl)-6,6,9-trimethyl-6H-benzo[c]chromen-1-ol | CHEMBL109393
Type:
Small organic molecule
Emp. Form.:
C25H34O2
Mol. Mass.:
366.5363
SMILES:
CCCCCCC(C)(C)c1cc(O)c-2c(OC(C)(C)c3ccc(C)cc-23)c1
Structure:
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