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Target
D(1A) dopamine receptor
Ligand
BDBM50269193
Substrate
n/a
Meas. Tech.
ChEMBL_527724 (CHEMBL975083)
IC50
81±n/a nM
Citation
 Sobarzo-Sánchez, EM; Arbaoui, J; Protais, P; Cassels, BK Halogenated boldine derivatives with enhanced monoamine receptor selectivity. J Nat Prod 63:480-4 (2000) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49429.75
Organism:
RAT
Description:
P18901
Residue:
446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM50269193
Synonyms:
3-Chloroboldine | CHEMBL524439
Type:
Small organic molecule
Emp. Form.:
C19H20ClNO4
Mol. Mass.:
361.819
SMILES:
COc1cc-2c(C[C@@H]3N(C)CCc4c(Cl)c(O)c(OC)c-2c34)cc1O |r|
Structure:
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