Reaction Details Report a problem with these data
Target
Cyclin-dependent kinase 5
Ligand
BDBM50250570
Substrate
n/a
Meas. Tech.
ChEMBL_548295 (CHEMBL1028365)
EC50
>250000±n/a nM
Citation
 Zapata-Torres, G; Opazo, F; Salgado, C; Muñoz, JP; Krautwurst, H; Mascayano, C; Sepúlveda-Boza, S; Maccioni, RB; Cassels, BK Effects of natural flavones and flavonols on the kinase activity of Cdk5. J Nat Prod 67:416-20 (2004) [PubMed]  Article 
Target
Name:
Cyclin-dependent kinase 5
Synonyms:
CDK5_RAT | Cdk5 | Cdkn5 | Cell division protein kinase 5 | PSSALRE
Type:
PROTEIN
Mol. Mass.:
33258.60
Organism:
Rattus norvegicus
Description:
ChEMBL_548295
Residue:
292
Sequence:
MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSLLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP
  
Inhibitor
Name:
BDBM50250570
Synonyms:
6-Hydroxy-5,7-dimethoxyflavone | CHEMBL464108
Type:
Small organic molecule
Emp. Form.:
C17H14O5
Mol. Mass.:
298.2901
SMILES:
COc1cc2oc(cc(=O)c2c(OC)c1O)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: