Reaction Details Report a problem with these data
Target
M-phase inducer phosphatase 2
Ligand
BDBM50261252
Substrate
n/a
Meas. Tech.
ChEMBL_531164 (CHEMBL974050)
IC50
400±n/a nM
Citation
 Schobert, R; Schlenk, A Tetramic and tetronic acids: an update on new derivatives and biological aspects. Bioorg Med Chem 16:4203-21 (2008) [PubMed]  Article 
Target
Name:
M-phase inducer phosphatase 2
Synonyms:
CDC25B | CDC25HU2 | Dual specificity phosphatase (CDC25B) | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2 (CDC25B) | MPIP2_HUMAN
Type:
Protein
Mol. Mass.:
64985.27
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
580
Sequence:
MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
  
Inhibitor
Name:
BDBM50261252
Synonyms:
CHEMBL511236 | [((R)-4-Hexadecanoyl-3-hydroxy-5-oxo-2,5-dihydro-furan-2-ylmethoxycarbonylimino)-methylene]-carbamic acid ethyl ester
Type:
Small organic molecule
Emp. Form.:
C26H40N2O8
Mol. Mass.:
508.6044
SMILES:
CCCCCCCCCCCCCCCC(=O)C1C(=O)O[C@H](COC(=O)N=C=NC(=O)OCC)C1=O |r|
Structure:
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