Reaction Details Report a problem with these data
Target
Phospholipase A2, membrane associated
Ligand
BDBM50262842
Substrate
n/a
Meas. Tech.
ChEMBL_489271 (CHEMBL990827)
IC50
60±n/a nM
Citation
 Oslund, RC; Cermak, N; Gelb, MH Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2. J Med Chem 51:4708-14 (2008) [PubMed]  Article 
Target
Name:
Phospholipase A2, membrane associated
Synonyms:
PA2GA_MOUSE | Pla2g2a
Type:
PROTEIN
Mol. Mass.:
16162.44
Organism:
Mus musculus
Description:
ChEMBL_352635
Residue:
146
Sequence:
MKVLLLLAASIMAFGSIQVQGNIAQFGEMIRLKTGKRAELSYAFYGCHCGLGGKGSPKDATDRCCVTHDCCYKSLEKSGCGTKLLKYKYSHQGGQITCSANQNSCQKRLCQCDKAAAECFARNKKTYSLKYQFYPNMFCKGKKPKC
  
Inhibitor
Name:
BDBM50262842
Synonyms:
Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetamide | CHEMBL514692
Type:
Small organic molecule
Emp. Form.:
C27H25N3O6S
Mol. Mass.:
519.569
SMILES:
CCc1c(C(=O)C(N)=O)c2c(OCC(=O)NS(=O)(=O)c3ccccc3)cccc2n1Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: