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Target
Phospholipase A2, membrane associated
Ligand
BDBM50274443
Substrate
n/a
Meas. Tech.
ChEMBL_537135 (CHEMBL989795)
IC50
60±n/a nM
Citation
 Oslund, RC; Cermak, N; Verlinde, CL; Gelb, MH Simplified YM-26734 inhibitors of secreted phospholipase A2 group IIA. Bioorg Med Chem Lett 18:5415-9 (2008) [PubMed]  Article 
Target
Name:
Phospholipase A2, membrane associated
Synonyms:
PA2GA_RAT | Phospholipase A2 group IIA | Pla2g2a
Type:
PROTEIN
Mol. Mass.:
16307.95
Organism:
Rattus norvegicus
Description:
ChEMBL_537135
Residue:
146
Sequence:
MKVLLLLAVVIMAFGSIQVQGSLLEFGQMILFKTGKRADVSYGFYGCHCGVGGRGSPKDATDWCCVTHDCCYNRLEKRGCGTKFLTYKFSYRGGQISCSTNQDSCRKQLCQCDKAAAECFARNKKSYSLKYQFYPNKFCKGKTPSC
  
Inhibitor
Name:
BDBM50274443
Synonyms:
(+ +)-1-{3-Dodecanoyl-2,4,6-trihydroxy-5-[(2R,4R)-7-hydroxy-2-(4-hydroxy-phenyl)-chroman-4-yl]-phenyl}-dodecan-1-one | CHEMBL452963
Type:
Small organic molecule
Emp. Form.:
C45H62O8
Mol. Mass.:
730.969
SMILES:
CCCCCCCCCCCC(=O)c1c(O)c([C@@H]2C[C@@H](Oc3cc(O)ccc23)c2ccc(O)cc2)c(O)c(C(=O)CCCCCCCCCCC)c1O |r|
Structure:
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