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Target
Cyclin-dependent kinase 2
Ligand
BDBM50275499
Substrate
n/a
Meas. Tech.
ChEMBL_497148 (CHEMBL1001228)
IC50
>10000±n/a nM
Citation
 Cheung, M; Harris, PA; Badiang, JG; Peckham, GE; Chamberlain, SD; Alberti, MJ; Jung, DK; Harris, SS; Bramson, NH; Epperly, AH; Stimpson, SA; Peel, MR The identification of pyrazolo[1,5-a]pyridines as potent p38 kinase inhibitors. Bioorg Med Chem Lett 18:5428-30 (2008) [PubMed]  Article 
Target
Name:
Cyclin-dependent kinase 2
Synonyms:
CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
33938.17
Organism:
Homo sapiens (Human)
Description:
P24941
Residue:
298
Sequence:
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
  
Inhibitor
Name:
BDBM50275499
Synonyms:
2-(4-fluorophenyl)-3-(4-pyridinyl)pyrazolo-[1,5-a]pyridine | CHEMBL485745
Type:
Small organic molecule
Emp. Form.:
C18H12FN3
Mol. Mass.:
289.3064
SMILES:
Fc1ccc(cc1)-c1nn2ccccc2c1-c1ccncc1
Structure:
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