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Target
Histidine kinase 4
Ligand
BDBM50274503
Substrate
n/a
Meas. Tech.
ChEMBL_537150 (CHEMBL989810)
EC50
24800±n/a nM
Citation
 Zatloukal, M; Gemrotová, M; Dolezal, K; Havlícek, L; Spíchal, L; Strnad, M Novel potent inhibitors of A. thaliana cytokinin oxidase/dehydrogenase. Bioorg Med Chem 16:9268-75 (2008) [PubMed]  Article 
Target
Name:
Histidine kinase 4
Synonyms:
AHK4 | AHK4_ARATH | CRE1 | Histidine kinase | RAW1 | WOL
Type:
PROTEIN
Mol. Mass.:
120723.86
Organism:
Arabidopsis thaliana
Description:
ChEMBL_537150
Residue:
1080
Sequence:
MRRDFVYNNNAMFNPLTTHYSSDMNWALNNHQEEEEEPRRIEISDSESLENLKSSDFYQLGGGGALNSSEKPRKIDFWRSGLMGFAKMQQQQQLQHSVAVKMNNNNNNDLMGNKKGSTFIQEHRALLPKALILWIIIVGFISSGIYQWMDDANKIRREEVLVSMCDQRARMLQDQFSVSVNHVHALAILVSTFHYHKNPSAIDQETFAEYTARTAFERPLLSGVAYAEKVVNFEREMFERQHNWVIKTMDRGEPSPVRDEYAPVIFSQDSVSYLESLDMMSGEEDRENILRARETGKAVLTSPFRLLETHHLGVVLTFPVYKSSLPENPTVEERIAATAGYLGGAFDVESLVENLLGQLAGNQAIVVHVYDITNASDPLVMYGNQDEEADRSLSHESKLDFGDPFRKHKMICRYHQKAPIPLNVLTTVPLFFAIGFLVGYILYGAAMHIVKVEDDFHEMQELKVRAEAADVAKSQFLATVSHEIRTPMNGILGMLAMLLDTELSSTQRDYAQTAQVCGKALIALINEVLDRAKIEAGKLELESVPFDIRSILDDVLSLFSEESRNKSIELAVFVSDKVPEIVKGDSGRFRQIIINLVGNSVKFTEKGHIFVKVHLAEQSKDESEPKNALNGGVSEEMIVVSKQSSYNTLSGYEAADGRNSWDSFKHLVSEEQSLSEFDISSNVRLMVSIEDTGIGIPLVAQGRVFMPFMQADSSTSRNYGGTGIGLSISKCLVELMRGQINFISRPHIGSTFWFTAVLEKCDKCSAINHMKKPNVEHLPSTFKGMKAIVVDAKPVRAAVTRYHMKRLGINVDVVTSLKTAVVAAAAFERNGSPLPTKPQLDMILVEKDSWISTEDNDSEIRLLNSRTNGNVHHKSPKLALFATNITNSEFDRAKSAGFADTVIMKPLRASMIGACLQQVLELRKTRQQHPEGSSPATLKSLLTGKKILVVDDNIVNRRVAAGALKKFGAEVVCAESGQVALGLLQIPHTFDACFMDIQMPQMDGFEATRQIRMMEKETKEKTNLEWHLPILAMTADVIHATYEECLKSGMDGYVSKPFEEENLYKSVAKSFKPNPISPSS
  
Inhibitor
Name:
BDBM50274503
Synonyms:
2-chloro-N-(3-fluorophenyl)-9H-purin-6-amine | CHEMBL520191
Type:
Small organic molecule
Emp. Form.:
C11H7ClFN5
Mol. Mass.:
263.658
SMILES:
Fc1cccc(Nc2nc(Cl)nc3nc[nH]c23)c1
Structure:
Search PDB for entries with ligand similarity: