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Target
Histidine kinase 3
Ligand
BDBM50274550
Substrate
n/a
Meas. Tech.
ChEMBL_537151 (CHEMBL989811)
EC50
33100±n/a nM
Citation
 Zatloukal, M; Gemrotová, M; Dolezal, K; Havlícek, L; Spíchal, L; Strnad, M Novel potent inhibitors of A. thaliana cytokinin oxidase/dehydrogenase. Bioorg Med Chem 16:9268-75 (2008) [PubMed]  Article 
Target
Name:
Histidine kinase 3
Synonyms:
AHK3 | AHK3_ARATH | Histidine kinase | ORE12
Type:
PROTEIN
Mol. Mass.:
116381.97
Organism:
Arabidopsis thaliana
Description:
ChEMBL_537151
Residue:
1036
Sequence:
MSLFHVLGFGVKIGHLFWMLCCWFVSWFVDNGIEDKSGLLVGSVGDLEKTKMTTLKKKNKMWFWNKISSSGLKIPSFSYQFLGSVKFNKAWWRKLVVVWVVFWVLVSIWTFWYFSSQAMEKRKETLASMCDERARMLQDQFNVSMNHVQAMSILISTFHHGKIPSAIDQRTFSEYTDRTSFERPLTSGVAYAMRVLHSEREEFERQQGWTIRKMYSLEQNPVHKDDYDLEALEPSPVQEEYAPVIFAQDTVSHVVSLDMLSGKEDRENVLRARSSGKGVLTAPFPLIKTNRLGVILTFAVYKRDLPSNATPKERIEATNGYLGGVFDIESLVENLLQQLASKQTILVNVYDITNHSQPISMYGTNVSADGLERVSPLIFGDPLRKHEMRCRFKQKPPWPVLSMVTSFGILVIALLVAHIIHATVSRIHKVEEDCDKMKQLKKKAEAADVAKSQFLATVSHEIRTPMNGVLGMLHMLMDTELDVTQQDYVRTAQASGKALVSLINEVLDQAKIESGKLELEEVRFDLRGILDDVLSLFSSKSQQKGVELAVYISDRVPDMLIGDPGRFRQILTNLMGNSIKFTEKGHIFVTVHLVDELFESIDGETASSPESTLSGLPVADRQRSWENFKAFSSNGHRSFEPSPPDINLIVSVEDTGVGIPVEAQSRIFTPFMQVGPSISRTHGGTGIGLSISKCLVGLMKGEIGFSSTPKVGSTFTFTAVFSNGMQPAERKNDNNQPIFSEFRGMKAVVVDHRPARAKVSWYHFQRLGIRVEVVPRVEQALHYLKIGTTTVNMILIEQEIWNREADDFIKKLQKDPLFLSPKLILLANSVESSISEALCTGIDPPIVIVKPLRASMLAATLQRGLGIGIREPPQHKGPPALILRNLLLGRKILIVDDNNVNLRVAAGALKKYGADVVCAESGIKAISLLKPPHEFDACFMDIQMPEMDGFEATRRIRDMEEEMNKRIKNGEALIVENGNKTSWHLPVLAMTADVIQATHEECLKCGMDGYVSKPFEAEQLYREVSRFFNSPSDTES
  
Inhibitor
Name:
BDBM50274550
Synonyms:
2-chloro-N-(4-methoxyphenyl)-9H-purin-6-amine | CHEMBL519009
Type:
Small organic molecule
Emp. Form.:
C12H10ClN5O
Mol. Mass.:
275.694
SMILES:
COc1ccc(Nc2nc(Cl)nc3nc[nH]c23)cc1
Structure:
Search PDB for entries with ligand similarity: