Target
Glutamate racemase
Ligand
BDBM50246527
Substrate
n/a
Meas. Tech.
ChEMBL_558148 (CHEMBL959077)
pH
8±n/a
IC50
7000±n/a nM
Comments
extracted
Citation
 Breault, GAComita-Prevoir, JEyermann, CJGeng, BPetrichko, RDoig, PGorseth, ENoonan, B Exploring 8-benzyl pteridine-6,7-diones as inhibitors of glutamate racemase (MurI) in gram-positive bacteria. Bioorg Med Chem Lett 18:6100-3 (2008) [PubMed]  Article 
Target
Name:
Glutamate racemase
Synonyms:
MURI_ENTFA | murI
Type:
PROTEIN
Mol. Mass.:
29478.43
Organism:
Enterococcus faecalis
Description:
ChEMBL_558148
Residue:
273
Sequence:
MSNQEAIGLIDSGVGGLTVLKEALKQLPNERLIYLGDTARCPYGPRPAEQVVQFTWEMADFLLKKRIKMLVIACNTATAVALEEIKAALPIPVVGVILPGARAAVKVTKNNKIGVIGTLGTIKSASYEIAIKSKAPTIEVTSLDCPKFVPIVESNQYRSSVAKKIVAETLQALQLKGLDTLILGCTHYPLLRPVIQNVMGSHVTLIDSGAETVGEVSMLLDYFDIAHTPEAPTQPHEFYTTGSAKMFEEIASSWLGIENLKAQQIHLGGNEND
  
Inhibitor
Name:
BDBM50246527
Synonyms:
2-(butylthio)-9-(4-nitrobenzyl)-9H-purin-6-amine | CHEMBL516506
Type:
Small organic molecule
Emp. Form.:
C16H18N6O2S
Mol. Mass.:
358.418
SMILES:
CCCCSc1nc(N)c2ncn(Cc3ccc(cc3)[N+]([O-])=O)c2n1
Structure:
Search PDB for entries with ligand similarity: