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Target
Serine/threonine-protein kinase Nek7
Ligand
BDBM50273636
Substrate
n/a
Meas. Tech.
ChEMBL_537120 (CHEMBL988952)
Kd
>40000±n/a nM
Citation
 Bamborough, P; Drewry, D; Harper, G; Smith, GK; Schneider, K Assessment of chemical coverage of kinome space and its implications for kinase drug discovery. J Med Chem 51:7898-914 (2008) [PubMed]  Article 
Target
Name:
Serine/threonine-protein kinase Nek7
Synonyms:
NEK kinase | NEK7 | NEK7_HUMAN
Type:
PROTEIN
Mol. Mass.:
34559.15
Organism:
Homo sapiens (Human)
Description:
ChEMBL_586832
Residue:
302
Sequence:
MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACTASS
  
Inhibitor
Name:
BDBM50273636
Synonyms:
4-(5-(4-fluorophenyl)-1H-pyrazol-3-ylamino)benzamide | CHEMBL511337
Type:
Small organic molecule
Emp. Form.:
C16H13FN4O
Mol. Mass.:
296.299
SMILES:
NC(=O)c1ccc(Nc2cc(n[nH]2)-c2ccc(F)cc2)cc1
Structure:
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