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Target
Fructose-1,6-bisphosphatase 1
Ligand
BDBM50266600
Substrate
n/a
Meas. Tech.
ChEMBL_516599 (CHEMBL988686)
IC50
4810±n/a nM
Citation
 Rudnitskaya, A; Huynh, K; Török, B; Stieglitz, K Novel heteroaromatic organofluorine inhibitors of fructose-1,6-bisphosphatase. J Med Chem 52:878-82 (2009) [PubMed]  Article 
Target
Name:
Fructose-1,6-bisphosphatase 1
Synonyms:
F16P1_MOUSE | Fbp | Fbp1 | Fbp3
Type:
PROTEIN
Mol. Mass.:
36912.07
Organism:
Mus musculus
Description:
ChEMBL_748173
Residue:
338
Sequence:
MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK
  
Inhibitor
Name:
BDBM50266600
Synonyms:
CHEMBL476823 | ethyl 3-(3,5-dimethyl-1H-pyrrol-2-yl)-4,4,4-trifluoro-3-hydroxybutanoate
Type:
Small organic molecule
Emp. Form.:
C12H16F3NO3
Mol. Mass.:
279.2555
SMILES:
CCOC(=O)CC(O)(c1[nH]c(C)cc1C)C(F)(F)F
Structure:
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