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Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM50267069
Substrate
n/a
Meas. Tech.
ChEMBL_563764 (CHEMBL993527)
IC50
6300±n/a nM
Citation
 Ottanà, R; Maccari, R; Ciurleo, R; Paoli, P; Jacomelli, M; Manao, G; Camici, G; Laggner, C; Langer, T 5-Arylidene-2-phenylimino-4-thiazolidinones as PTP1B and LMW-PTP inhibitors. Bioorg Med Chem 17:1928-37 (2009) [PubMed]  Article 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
LTP1 | PPAL_YEAST
Type:
PROTEIN
Mol. Mass.:
18678.01
Organism:
Saccharomyces cerevisiae
Description:
ChEMBL_563764
Residue:
161
Sequence:
MTIEKPKISVAFICLGNFCRSPMAEAIFKHEVEKANLENRFNKIDSFGTSNYHVGESPDHRTVSICKQHGVKINHKGKQIKTKHFDEYDYIIGMDESNINNLKKIQPEGSKAKVCLFGDWNTNDGTVQTIIEDPWYGDIQDFEYNFKQITYFSKQFLKKEL
  
Inhibitor
Name:
BDBM50267069
Synonyms:
4-{[4-Oxo-5-(4-phenoxybenzylidene)-2-phenyliminothiazolidin-3-yl]methyl}benzoic acid | CHEMBL478274
Type:
Small organic molecule
Emp. Form.:
C30H22N2O4S
Mol. Mass.:
506.572
SMILES:
OC(=O)c1ccc(CN2\C(S\C(=C/c3ccc(Oc4ccccc4)cc3)C2=O)=N\c2ccccc2)cc1
Structure:
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