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Target
Testis-specific serine/threonine-protein kinase 1
Ligand
BDBM50279384
Substrate
n/a
Meas. Tech.
ChEMBL_545769 (CHEMBL1027664)
IC50
98000±n/a nM
Citation
 Zhang, L; Yan, Y; Liu, Z; Abliz, Z; Liu, G Identification of peptide substrate and small molecule inhibitors of testis-specific serine/threonine kinase1 (TSSK1) by the developed assays. J Med Chem 52:4419-28 (2009) [PubMed]  Article 
Target
Name:
Testis-specific serine/threonine-protein kinase 1
Synonyms:
SPOGA1 | SPOGA4 | STK22A | STK22D | TSSK1 | TSSK1B | TSSK1_HUMAN | Testis-specific serine/threonine-protein kinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41624.03
Organism:
Homo sapiens (Human)
Description:
gi_14042947
Residue:
367
Sequence:
MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWTPEPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQPPETRAQ
  
Inhibitor
Name:
BDBM50279384
Synonyms:
CHEMBL521476 | N-(4-(7-methyl-6-oxo-1-(3-phenylpropyl)-5,6-dihydro-1H-imidazo[4,5-g]quinoxalin-2-yl)phenyl)acetamide
Type:
Small organic molecule
Emp. Form.:
C27H25N5O2
Mol. Mass.:
451.5197
SMILES:
CC(=O)Nc1ccc(cc1)-c1nc2cc3[nH]c(=O)c(C)nc3cc2n1CCCc1ccccc1
Structure:
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