Reaction Details Report a problem with these data
Target
Thromboxane A2 receptor
Ligand
BDBM50280718
Substrate
n/a
Meas. Tech.
ChEBML_209598
Kd
19±n/a nM
Citation
 Misra, RN; Harris, DN; Michel, IM; Goldenberg, HJ; Webb, ML; Brown, BR Interphenylene phenyl oxazoles: novel, potent thromboxane receptor antagonists Bioorg Med Chem Lett 2:937-940 (1992)    Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50280718
Synonyms:
3-(2-{2-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2-yl]-benzyl}-phenyl)-propionic acid | CHEMBL170747
Type:
Small organic molecule
Emp. Form.:
C30H36N2O4
Mol. Mass.:
488.6178
SMILES:
OC(=O)CCc1ccccc1Cc1ccccc1-c1nc(co1)C(=O)NCCCCC1CCCCC1
Structure:
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