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Target
Chymotrypsin-like elastase family member 2A
Ligand
BDBM50281090
Substrate
n/a
Meas. Tech.
ChEMBL_194721 (CHEMBL807702)
IC50
400±n/a nM
Citation
 Adonias, M; Anayaba, J; Cámara, J; Canet, E; Gateau-Olesker, A; Gero, SD; Grande, M; Hernando, JI Enantioselective synthesis and antielastase activity of 1,3,4-trisubstituted and 3,4-disubstituted β-lactam antibiotics Bioorg Med Chem Lett 3:2547-2552 (1993)    Article 
Target
Name:
Chymotrypsin-like elastase family member 2A
Synonyms:
CEL2A_RAT | Cela2a | Ela2 | Ela2a | Elastase 2A | Elastase-2 | Elastase-2A
Type:
PROTEIN
Mol. Mass.:
28894.94
Organism:
Rattus norvegicus
Description:
ChEMBL_194721
Residue:
271
Sequence:
MIRTLLLSALVAGALSCGYPTYEVQHDVSRVVGGQEASPNSWPWQVSLQYLSSGKWHHTCGGSLVANNWVLTAAHCISNSRTYRVLLGRHSLSTSESGSLAVQVSKLVVHEKWNAQKLSNGNDIALVKLASPVALTSKIQTACLPPAGTILPNNYPCYVTGWGRLQTNGATPDVLQQGRLLVVDYATCSSASWWGSSVKTNMVCAGGDGVTSSCNGDSGGPLNCQASNGQWQVHGIVSFGSTLGCNYPRKPSVFTRVSNYIDWINSVIAKN
  
Inhibitor
Name:
BDBM50281090
Synonyms:
(3S,4R)-1-Acetyl-3-methoxy-4-phenyl-azetidin-2-one | CHEMBL84758
Type:
Small organic molecule
Emp. Form.:
C12H13NO3
Mol. Mass.:
219.2365
SMILES:
CO[C@H]1[C@H](N(C(C)=O)C1=O)c1ccccc1
Structure:
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