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Target
Chymotrypsin-like elastase family member 2A
Ligand
BDBM50281094
Substrate
n/a
Meas. Tech.
ChEBML_152479
IC50
>200000±n/a nM
Citation
 Adonias, M; Anayaba, J; Cámara, J; Canet, E; Gateau-Olesker, A; Gero, SD; Grande, M; Hernando, JI Enantioselective synthesis and antielastase activity of 1,3,4-trisubstituted and 3,4-disubstituted β-lactam antibiotics Bioorg Med Chem Lett 3:2547-2552 (1993)    Article 
Target
Name:
Chymotrypsin-like elastase family member 2A
Synonyms:
CEL2A_PIG | CELA2A | ELA2 | ELA2A | Elastase 2A | Elastase-2 | Elastase-2A | Pancreatic elastase
Type:
PROTEIN
Mol. Mass.:
28705.23
Organism:
Sus scrofa
Description:
ChEMBL_156951
Residue:
269
Sequence:
MIRALLLSTLVAGALSCGLPANLPQLPRVVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGGDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVIANN
  
Inhibitor
Name:
BDBM50281094
Synonyms:
(3R,4R)-3-Butyl-1-[(R)-[1,3]dithian-2-yl-(2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-methyl]-4-((E)-1-methyl-2-phenyl-vinyl)-azetidin-2-one | CHEMBL82333
Type:
Small organic molecule
Emp. Form.:
C31H45NO5S2
Mol. Mass.:
575.823
SMILES:
CCCC[C@@H]1[C@@H](N([C@H](C2OC(C)(C)OC2C2COC(C)(C)O2)C2SCCCS2)C1=O)C(\C)=C\c1ccccc1
Structure:
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