Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50281439
Substrate
n/a
Meas. Tech.
ChEBML_201272
Ki
232±n/a nM
Citation
 Schow, SR; Tam, SW Novel sigma receptor ligands 1. Bioorg Med Chem Lett 3:215-220 (1993)    Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25124.85
Organism:
Homo sapiens (Human)
Description:
Q99720
Residue:
223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50281439
Synonyms:
8-(3-Chloro-benzyl)-3-phenyl-1-oxa-8-aza-spiro[4.5]dec-2-en-4-one; hydrochloride | CHEMBL538248
Type:
Small organic molecule
Emp. Form.:
C21H20ClNO2
Mol. Mass.:
353.842
SMILES:
Clc1cccc(CN2CCC3(CC2)OC=C(C3=O)c2ccccc2)c1 |c:15|
Structure:
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