Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50281501
Substrate
n/a
Meas. Tech.
ChEBML_62242
Ki
322±n/a nM
Citation
 Wustrow, DJ; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG 4-Aryltetrahydropyridines as selective σ ligands Bioorg Med Chem Lett 3:277-280 (1993)    Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50281501
Synonyms:
1'-(4-Pyridin-4-yl-butyl)-1',2',3',6'-tetrahydro-[2,4']bipyridinyl | CHEMBL94844
Type:
Small organic molecule
Emp. Form.:
C19H23N3
Mol. Mass.:
293.406
SMILES:
C(CCc1ccncc1)CN1CCC(=CC1)c1ccccn1 |c:14|
Structure:
Search PDB for entries with ligand similarity: