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Target
5-hydroxytryptamine receptor 5A
Ligand
BDBM50284084
Substrate
n/a
Meas. Tech.
ChEMBL_201045 (CHEMBL804074)
Ki
287±n/a nM
Citation
 Haadsma-Svensson, SR; Smith, MW; Lin, CH; Duncan, JN; Sonesson, C; Wikström, H; Waters, N; Carlsson, A; Svensson, K Synthesis and biological activity of C-5 modified derivatives of (+)-AJ76 and (+)-UH232: Increased dopamine D3 receptor preference and improved pharmacokinetic properties Bioorg Med Chem Lett 4:689-694 (1994)    Article 
Target
Name:
5-hydroxytryptamine receptor 5A
Synonyms:
5-HT-5 | 5-HT-5A | 5-hydroxytryptamine receptor 5 (5-HT5) | 5-hydroxytryptamine receptor 5A (5-HT5A) | 5HT5A_HUMAN | HTR5A | Serotonin (5-HT) receptor | Serotonin receptor 5A
Type:
Enzyme
Mol. Mass.:
40266.25
Organism:
Homo sapiens (Human)
Description:
P47898
Residue:
357
Sequence:
MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
  
Inhibitor
Name:
BDBM50284084
Synonyms:
(5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-naphthalene-1-carboxylic acid methyl ester | CHEMBL161507
Type:
Small organic molecule
Emp. Form.:
C16H23NO2
Mol. Mass.:
261.3593
SMILES:
CCCN[C@@H]1CCc2c(cccc2C(=O)OC)[C@@H]1C
Structure:
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