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Target
Cathepsin B
Ligand
BDBM50284944
Substrate
n/a
Meas. Tech.
ChEBML_47631
Ki
367000±n/a nM
Citation
 Albeck, A; Persky, R; Kliper, S Design of a new selective cysteine protease inactivator and its mechanistic implications Bioorg Med Chem Lett 5:1767-1772 (1995)    Article 
Target
Name:
Cathepsin B
Synonyms:
APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1
Type:
Enzyme
Mol. Mass.:
37819.69
Organism:
Homo sapiens (Human)
Description:
gi_63102437
Residue:
339
Sequence:
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
  
Inhibitor
Name:
BDBM50284944
Synonyms:
((S)-1-(S)-Oxiranyl-2-phenyl-ethyl)-carbamic acid benzyl ester | CHEMBL298965
Type:
Small organic molecule
Emp. Form.:
C18H19NO3
Mol. Mass.:
297.3484
SMILES:
O=C(N[C@@H](Cc1ccccc1)[C@H]1CO1)OCc1ccccc1
Structure:
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