Reaction Details Report a problem with these data
Target
Papain
Ligand
BDBM50284944
Substrate
n/a
Meas. Tech.
ChEMBL_152659 (CHEMBL761585)
Ki
0.208000±n/a nM
Citation
 Albeck, A; Persky, R; Kliper, S Design of a new selective cysteine protease inactivator and its mechanistic implications Bioorg Med Chem Lett 5:1767-1772 (1995)    Article 
Target
Name:
Papain
Synonyms:
Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I
Type:
Enzyme
Mol. Mass.:
38923.01
Organism:
Carica papaya
Description:
Papain was purchased from Sigma, Germany.
Residue:
345
Sequence:
MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNEYSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYGPNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
  
Inhibitor
Name:
BDBM50284944
Synonyms:
((S)-1-(S)-Oxiranyl-2-phenyl-ethyl)-carbamic acid benzyl ester | CHEMBL298965
Type:
Small organic molecule
Emp. Form.:
C18H19NO3
Mol. Mass.:
297.3484
SMILES:
O=C(N[C@@H](Cc1ccccc1)[C@H]1CO1)OCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: