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Target
Cholesteryl ester transfer protein
Ligand
BDBM50285081
Substrate
n/a
Meas. Tech.
ChEBML_48937
IC50
34000±n/a nM
Citation
 Chackalamannil, S; Xia, Y; Wang, Y; Tsai, H; Czarniecki, M; Wang, S; Clemmons, A; Ahn, HS; Boykow, G Novel inhibitors of cholesteryl ester transfer protein Bioorg Med Chem Lett 5:2005-2010 (1995)    Article 
Target
Name:
Cholesteryl ester transfer protein
Synonyms:
CETP | CETP_HUMAN | Cholesteryl ester transfer protein (CETP) | Lipid transfer protein I
Type:
Enzyme
Mol. Mass.:
54751.53
Organism:
Homo sapiens (Human)
Description:
P11597
Residue:
493
Sequence:
MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDITGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTTAWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWIKQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVITASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRLMLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSSVMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSESVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLS
  
Inhibitor
Name:
BDBM50285081
Synonyms:
4-((S)-2,5,5,8a-Tetramethyl-3,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-ylmethyl)-benzene-1,2,3-triol | CHEMBL64743
Type:
Small organic molecule
Emp. Form.:
C21H30O3
Mol. Mass.:
330.4611
SMILES:
CC1=C(Cc2ccc(O)c(O)c2O)[C@@]2(C)CCCC(C)(C)C2CC1 |c:1|
Structure:
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