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Target
Genome polyprotein
Ligand
BDBM50285093
Substrate
n/a
Meas. Tech.
ChEBML_161258
IC50
>80000±n/a nM
Citation
 Kaldor, SW; Hammond, M; Dressman, BA; Labus, JM; Chadwell, FW; Kline, AD; Heinz, BA Glutamine-derived aldehydes for the inhibition of human rhinovirus 3C protease Bioorg Med Chem Lett 5:2021-2026 (1995)    Article 
Target
Name:
Genome polyprotein
Synonyms:
Human rhinovirus A protease | Human rhinovirus B 3A protease
Type:
PROTEIN
Mol. Mass.:
44361.04
Organism:
Human rhinovirus B
Description:
ChEMBL_158953
Residue:
401
Sequence:
AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMSAIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIANIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVITTGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDRNEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYNYPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQTIHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
  
Inhibitor
Name:
BDBM50285093
Synonyms:
4-[2-(3-Methyl-butyrylamino)-3-phenyl-propionylamino]-5-oxo-pentanoic acid amide | CHEMBL61839
Type:
Small organic molecule
Emp. Form.:
C19H27N3O4
Mol. Mass.:
361.4354
SMILES:
CC(C)CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C=O
Structure:
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