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Target
Prostaglandin-H2 D-isomerase
Ligand
BDBM50008029
Substrate
n/a
Meas. Tech.
ChEBML_158156
IC50
3500±n/a nM
Citation
 Kumar, V; Alexander, MD; Bell, MR; Eissenstat, MA; Casiano, FM; Chippari, SM; Haycock, DA; Luttinger, DA; Kuster, JE; Miller, MS; Stevenson, JI; Ward, SJ Morpholinoalkylindenes as antinociceptive agents: Novel cannabinoid receptor agonists Bioorg Med Chem Lett 5:381-386 (1995)    Article 
Target
Name:
Prostaglandin-H2 D-isomerase
Synonyms:
PTGDS_MOUSE | Ptgds
Type:
PROTEIN
Mol. Mass.:
21069.88
Organism:
Mus musculus
Description:
ChEMBL_158158
Residue:
189
Sequence:
MAALRMLWMGLVLLGLLGFPQTPAQGHDTVQPNFQQDKFLGRWYSAGLASNSSWFREKKAVLYMCKTVVAPSTEGGLNLTSTFLRKNQCETKIMVLQPAGAPGHYTYSSPHSGSIHSVSVVEANYDEYALLFSRGTKGPGQDFRMATLYSRTQTLKDELKEKFTTFSKAQGLTEEDIVFLPQPDKCIQE
  
Inhibitor
Name:
BDBM50008029
Synonyms:
(4-Methoxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone | (s-cis) -(4-Methoxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone | CHEMBL13178 | PRAVADOLINE
Type:
Small organic molecule
Emp. Form.:
C23H26N2O3
Mol. Mass.:
378.4641
SMILES:
COc1ccc(cc1)C(=O)c1c(C)n(CCN2CCOCC2)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: