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Target
Mu-type opioid receptor
Ligand
BDBM50287331
Substrate
n/a
Meas. Tech.
ChEBML_136063
IC50
0.560000±n/a nM
Citation
 Hutchinson, I; Archer, S; Hill, KP; Bidlack, JM Synthesis and opioid binding properties of 2-chloroacrylamido derivatives of 7,8-dihydromorphinans Bioorg Med Chem Lett 6:1563-1566 (1996)    Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
MOR-1 | Mu opioid receptor | OPIATE Mu | OPRM1 | OPRM_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45038.37
Organism:
CALF
Description:
OPIATE Mu 2 0 CALF::P79350
Residue:
401
Sequence:
MDSGAVPTNASNCTDPFTHPSSCSPAPSPSSWVNFSHLEGNLSDPCGPNRTELGGSDRLCPSAGSPSMITAIIIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDLRTPRNAKIINICNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPILIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETTPLP
  
Inhibitor
Name:
BDBM50287331
Synonyms:
1N-[10-hydroxy-4-methyl-(13R,14R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yl]-2-chloroacrylamide | CHEMBL41366
Type:
Small organic molecule
Emp. Form.:
C20H23ClN2O3
Mol. Mass.:
374.861
SMILES:
CN1CCC23[C@H]4Oc5c2c(CC1C3CC[C@H]4NC(=O)C(Cl)=C)ccc5O |THB:7:8:12:1.3.2,0:1:12:8.9.10|
Structure:
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