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Target
Histidinol dehydrogenase, chloroplastic
Ligand
BDBM50267342
Substrate
n/a
Meas. Tech.
ChEMBL_923891 (CHEMBL3082926)
IC50
1000±n/a nM
Citation
 Dancer, JE; Ford, MJ; Hamilton, K; Kilkelly, M; Lindell, SD; O'Mahony, MJ; Saville-Stones, EA Synthesis of potent inhibitors of histidinol dehydrogenase Bioorg Med Chem Lett 6:2131-2136 (1996)    Article 
Target
Name:
Histidinol dehydrogenase, chloroplastic
Synonyms:
HDH | HISX_BRAOC | Histidinol dehydrogenase
Type:
PROTEIN
Mol. Mass.:
50957.92
Organism:
Brassica oleracea var. capitata
Description:
EBI_100278
Residue:
469
Sequence:
MSFDLSRLSLTSSPRLSFLTRTATKKGFVRCSMKSYRLSELSFSQVENLKARPRIDFSSIFTTVNPIIDAVRSKGDTAVKEYTERFDKVQLNKVVEDVSELDIPELDSAVKEAFDVAYDNIYAFHFAQMSTEKSVENMKGVRCKRVSRSIGSVGLYVPGGTAVLPSTALMLAIPAQIAGCKTVVLATPPTKEGSICKEVLYCAKRAGVTHILKAGGAQAIAAMAWGTDSCPKVEKIFGPGNQYVTAAKMILQNSEAMVSIDMPAGPSEVLVIADEHASPVYIAADLLSQAEHGPDSQVVLVVVGDGVNLKAIEEEIAKQCKSLPRGEFASKALSHSFTVFARDMIEAITFSNLYAPEHLIINVKDAEKWEGLIENAGSVFIGPWTPESVGDYASGTNHVLPTYGYARMYSGVSLDSFLKFMTVQSLTEEGLRNLGPYVATMAEIEGLDAHKRAVTLRLKDIEAKQTQTK
  
Inhibitor
Name:
BDBM50267342
Synonyms:
(S)-3-Amino-4-(1H-imidazol-4-yl)-1-(4-methoxy-phenyl)-butan-2-one; dihydrochloride | (S)-3-amino-4-(1H-imidazol-4-yl)-1-(4-methoxyphenyl)butan-2-one dihydrochloride | CHEMBL477467
Type:
Small organic molecule
Emp. Form.:
C14H17N3O2
Mol. Mass.:
259.3037
SMILES:
COc1ccc(CC(=O)[C@@H](N)Cc2cnc[nH]2)cc1 |r|
Structure:
Search PDB for entries with ligand similarity: