Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50288747
Substrate
n/a
Meas. Tech.
ChEBML_30918
Ki
>38500±n/a nM
Citation
 Poulsen, SA; Quin, RJ Pyrazolo[3,4-d]pyrimidines: C4, C6 substitution leads to adenosine A1 receptor selectivity Bioorg Med Chem Lett 6:357-360 (1996)    Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
45015.65
Organism:
Rattus norvegicus (rat)
Description:
Rat A2A receptors expressed in CHO cells.
Residue:
410
Sequence:
MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
  
Inhibitor
Name:
BDBM50288747
Synonyms:
2-(1-Phenyl-4-propylsulfanyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-butyramide | CHEMBL122876
Type:
Small organic molecule
Emp. Form.:
C18H21N5OS2
Mol. Mass.:
387.522
SMILES:
CCCSc1nc(SC(CC)C(N)=O)nc2n(ncc12)-c1ccccc1
Structure:
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