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Target
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Ligand
BDBM50289143
Substrate
n/a
Meas. Tech.
ChEBML_205196
Ki
35±n/a nM
Citation
 Abell, AD; Brandt, M; Levy, MA; Holt, DA The preparation and evaluation of (+/-)-trans-1-Diazo-8-methoxy-4a-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-2-one as an inhibitor of human type-1 steroid 5α-reductase Bioorg Med Chem Lett 6:883-884 (1996)    Article 
Target
Name:
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Synonyms:
S5A1_RAT | Srd5a1 | Steroid 5-alpha-reductase | Steroid 5-alpha-reductase 1
Type:
PROTEIN
Mol. Mass.:
29788.29
Organism:
Rattus norvegicus
Description:
ChEMBL_1441437
Residue:
259
Sequence:
MVPLMELDELCLLDMLVYLEGFMAFVSIVGLRSVGSPYGRYSPQWPGIRVPARPAWFIQELPSMAWPLYEYIRPAAARLGNLPNRVLLAMFLIHYVQRTLVFPVLIRGGKPTLLVTFVLAFLFCTFNGYVQSRYLSQFAVYAEDWVTHPCFLTGFALWLVGMVINIHSDHILRNLRKPGETGYKIPRGGLFEYVSAANYFGELVEWCGFALASWSLQGVVFALFTLSTLLTRAKQHHQWYHEKFEDYPKSRKILIPFVL
  
Inhibitor
Name:
BDBM50289143
Synonyms:
(5R,10R,14S)-17-(2-Hydroxy-1-methyl-ethyl)-10-methyl-13-(R)-methyl-3-oxo-hexadecahydro-cyclopenta[a]phenanthrene-4-diazonium | CHEMBL3138301
Type:
Small organic molecule
Emp. Form.:
C22H34N2O2
Mol. Mass.:
358.5176
SMILES:
[H][C@@]12CC[C@H](C(C)CO)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])C(=[N+]=[N-])C(=O)CC[C@]12C
Structure:
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