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Target
Prolyl endopeptidase
Ligand
BDBM50289632
Substrate
n/a
Meas. Tech.
ChEBML_157480
IC50
216±n/a nM
Citation
 Károly, K; Sándor, Es; Edit, S; Miklós, F; Judit, S; Benjámin, P; Andrea, S; István, H Prolyl endopeptidase inhibitors1: N-acyl derivatives of L-thioproline-pyrrolidine Bioorg Med Chem Lett 7:1701-1704 (1997)    Article 
Target
Name:
Prolyl endopeptidase
Synonyms:
PPCE_RAT | Prep
Type:
PROTEIN
Mol. Mass.:
80731.99
Organism:
Rattus norvegicus
Description:
ChEMBL_1336163
Residue:
710
Sequence:
MLSFQYPDVYRDETSVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNTLSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFTCMAWTHDGKGMFYNSYPQQDGKSDGTETSTNLHQKLCYHVLGTDQSEDVLCAEFPDEPKWMGGAELSDDGRYVLLSIWEGCDPVNRLWYCDLQQGSNGINGILKWVKLIDNFEGEYDYITNEGTVFTFKTNRNSPNYRLINIDFTDPDESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLRNVKNILQLHDLTTGALLKTFPLDVGSVVGYSGRKKDSEIFYQFTSFLSPGVIYHCDLTREELEPRVFREVTVKGIDASDYQTIQVFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTTSKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKFTIGHAWTTDYGCSDSKQHFEWLLKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQSNPLLIHVDTKAGHGPGKPTAKVIEEVSDMFAFIARCLNIEWIQ
  
Inhibitor
Name:
BDBM50289632
Synonyms:
1-[(R)-4-(Pyrrolidine-1-carbonyl)-thiazolidin-3-yl]-hexadecan-1-one | CHEMBL50765
Type:
Small organic molecule
Emp. Form.:
C24H44N2O2S
Mol. Mass.:
424.683
SMILES:
CCCCCCCCCCCCCCCC(=O)N1CSC[C@H]1C(=O)N1CCCC1
Structure:
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