Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50047174
Substrate
n/a
Meas. Tech.
ChEBML_29422
Ki
3300±n/a nM
Citation
 Shimada, J; Koike, N; Nonaka, H; Shiozaki, S; Yanagawa, K; Kanda, T; Kobayashi, H; Ichimura, M; Nakamura, J; Kase, H; Suzuki, F Adenosine A2A antagonists with potent anti-cataleptic activity Bioorg Med Chem Lett 7:2349-2352 (1997)    Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor | AA1R_CAVPO | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor | Adenosine Receptor A1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36501.39
Organism:
GUINEA PIG
Description:
ADENOSINE A1 ADORA1 GUINEA PIG::P47745
Residue:
326
Sequence:
MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD
  
Inhibitor
Name:
BDBM50047174
Synonyms:
7-Methyl-1,3-dipropyl-8-[(E)-2-(2,4,5-trimethoxy-phenyl)-vinyl]-3,7-dihydro-purine-2,6-dione | 7-Methyl-1,3-dipropyl-8-[2-(2,4,5-trimethoxy-phenyl)-vinyl]-3,7-dihydro-purine-2,6-dione | CHEMBL283847
Type:
Small organic molecule
Emp. Form.:
C23H30N4O5
Mol. Mass.:
442.5081
SMILES:
CCCn1c2nc(\C=C\c3cc(OC)c(OC)cc3OC)n(C)c2c(=O)n(CCC)c1=O
Structure:
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