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Target
5-hydroxytryptamine receptor 5B
Ligand
BDBM50026385
Substrate
n/a
Meas. Tech.
ChEBML_201219
Ki
67±n/a nM
Citation
 Baxter, EW; Reitz, AB Hindered rotation congeners of mazapertine: High affinity ligands for the 5-HT1A receptor Bioorg Med Chem Lett 7:763-768 (1997)    Article 
Target
Name:
5-hydroxytryptamine receptor 5B
Synonyms:
5-HT5B | 5-hydroxytryptamine receptor 5B | 5HT5B_RAT | 5ht5b | Htr5b | Serotonin (5-HT) receptor | Serotonin 5b (5-HT5b) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41141.95
Organism:
RAT
Description:
5-HT5B 0 RAT::P35365
Residue:
370
Sequence:
MEVSNLSGATPGIAFPPGPESCSDSPSSGRSMGSTPGGLILSGREPPFSAFTVLVVTLLVLLIAATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAALVMPLSLVSELSAGRRWQLGRSLCHVWISFDVLCCTASIWNVAAIALDRYWTITRHLQYTLRTRRRASALMIAITWALSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFSTCGAFYVPLAVVLFVYWKIYKAAKFRFGRRRRAVVPLPATTQAKEAPQESETVFTARCRATVAFQTSGDSWREQKEKRAAMMVGILIGVFVLCWIPFFLTELVSPLCACSLPPIWKSIFLWLGYSNSFFNPLIYTAFNKNYNNAFKSLFTKQR
  
Inhibitor
Name:
BDBM50026385
Synonyms:
9-Trifluoromethyl-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline | CHEMBL351530
Type:
Small organic molecule
Emp. Form.:
C13H15F3N2
Mol. Mass.:
256.2668
SMILES:
FC(F)(F)c1ccc2CCC3CNCCN3c2c1
Structure:
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